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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f901ca1f515a3bea1d4deddd0493712708f803f8822d5f37b5994b29b85dcf' 
  AND token = 'p+gVE7aP4HgRTizzxBWTDjoefXYKs+XFn7KAB14apvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}