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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a680e5bcfd60ade7c09fc0c916b1944fd798adce344f635af2563da2c19a138' 
  AND token = 'D0NysY3nVitqsLEv/JE+NevM59PEYMo3F/i15COrXUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}