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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dfddee26e7d3861608cb7ea10d750abf1009333e9531f40a146fad1b9e7066f' 
  AND token = 'M+bmY5H8jE+8tjeWTWbQ8U+0DMXQ4rlDJ3W27ZiZRAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}