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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886691ef9024666141fd143f1cd8e69f1ae7ab9da7595f099f2d116caab17de5' 
  AND token = 'CMg0ZsBKJv/yaJHnRaOkHjIh3wE7XOJSuEtOe8FO2js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}