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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df4dd88fae6d5b0320497c58e129c4b626091edff6563c69cf51dae650cce61' 
  AND token = '6p3Vo0+Grvc0gMtlZH02RcOEfwuNyEPwO6yKaIejDyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}