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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4410ff4e79cd82d18d5e11285286d8e3d0efe8d177b2e0082ef38c16017ae6' 
  AND token = '1kk4OPYNETtSJPdD72JYEnwvlcMPkMpuKWuomcLRcm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}