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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f3f03fb635bbcee4d4e027b04057be17a9b7310f9a4d05a1076b70cd29a9059' 
  AND token = 'WYyZAR+rdDoEAFC9/eq33C35jQhWAoXU9xiUcf7MmF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}