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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3acae7d0ad5e6231dfbfa6a884291892b6646bd1ddd0d97de9f7e29c9523b21' 
  AND token = 'oer8vLCFAEgVPyL/D5ArA/U0h7CnhgTfwAwmb+kOWFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}