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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d2c6a5e64c523753288e3192336dccce0ecf471741550a76b9aaf10d5f4672' 
  AND token = 'oTLoGoU80huzK7sIknLa5D85+Ix/YMPmtE3KfBYJDts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}