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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4442fb500d6c25068b99d8b220726a1c3629278316064894bb90666f1df839' 
  AND token = 'vnlK6DTY5a/7vcEHr1mkgkCQBFuxX684eSdTchkdz4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}