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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c35e23e7a51b02a895b1313d3ac9519507eff6420f1a05f0e5d4e73b1c43f272' 
  AND token = '+4kPeRs1qEFW1xlZJYAFHs22TCPJTagInXu8PHQX20c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}