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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b00f16df6654c15782d37be05f3453aef993af7a4b4930d8e8a93d0a8e8806a' 
  AND token = 'zerMazAxpMP6hgg/F6dmd9B+qfHQWsPcSOSJ/zc9K3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}