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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b53bf48b24388b05eb9f90bb2449a70a057c10329bd02b499c5751580a9a135' 
  AND token = 'OlCpXVfC6pZzFCINtL5s1s+eZw9oOAuRsQlsByrhGDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}