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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ef8d274e8c66a2e119a618f8d43c8f42d662fade5195e5fbadb72b48622cb4' 
  AND token = '9ZTx86Boo5Ps2em80Y2EjG5Rxjyl5/Ddwh3vWnYtz4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}