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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb5f5a8d07bb42f9128596ab9c8fc109568af6ed43ae50f6725aa25f86c7e2b' 
  AND token = '8KpeXyXMmvAFIu7y+6KP9v4m3ltCUKCR4bNrrrJ0vYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}