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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df5e545c3f56be3af638b545cde8dac32c5f040aad1e43641e795d7fbefc57d0' 
  AND token = 'anhyrvLn1+2VL/6c93ZY8YRo69tpFllTr1jKt4JxX50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}