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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a7d3e3e46916b453b157082e2fa44acccec1c8c0add027dd1c209b01002772' 
  AND token = '9HmiLA+53APzfjeB3lOrKy/7j8J+izqvkFFRbFY4AuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}