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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850403b9ee4f54fe3b9b39d82b072f15fed56edbd292e8defd132eb1b728ca52' 
  AND token = 'gBz7kkIU5w2nXLlhxgMrF0OjTuQ886W/jy3XYuRPJUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}