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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b08f0e4228b26aca717bb69942ae03374ca81d8a919864e1fd1d17940ccb00' 
  AND token = 'fxedPPS24+otbJphNZffe1NVm9yQ70ieKw49hXmld48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}