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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a63fb7dc7adfe4a076cf1134d2ff7cbdf07b73efa4313ee166df8b21e144291' 
  AND token = '0+JxlGQeHyGYA0AJg6Yfk2T7xt2D3/M1hBFEW8s52gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}