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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ded1e9893d44bdbff863adb0a812f6bf9591da1d9f06229bdaff4708f71a3e' 
  AND token = 'EY77RKRj6WQ6P1Eh1beTWiUBqMG2GwBQF2OrhnZGSa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}