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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bec630c3db0d8a0e9cb04384ccb55aaa0cf95bd98425ca2e0bf65194828e221' 
  AND token = 'PneZDHkL2oOmzGBg92P8fP+Yj1G90eeBGWm1eDHrd4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}