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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b834916e52188b7f06980e168115beb922dcac48491a377139d38f867fabe60' 
  AND token = 'm0GI6WMXX9VPwPt1BbpSnob4iBA3HtJb26l4c1EsHiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}