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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed18ae5bd3e27f6e3625b728c02e02f1beb8b3f7e46f396fc61f41f4fc94cd1e' 
  AND token = 'PRL66WFIuGdqrkm4+MYwoXqpo2SdJA+CBIiDbq+YMrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}