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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80900cd80857aebe8deba7bca65534af40f0dc4ec33a2f10691a29c2e3c2f42c' 
  AND token = 'iIxK5iMd2YTf6RejnwGxHW3dnx/FNwgZVUq+maPo/f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}