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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1494a4782b4348edeed1890b0a614ace0011ac8156242cf0f59b53fb766f15b0' 
  AND token = '3DW2s/mtTLw2qIpUS1Fbt28h19AcBWj+HijQcVkZ9JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}