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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a826a0dd12dc3877cff04b75d410d9d0563c955a514a6619a5afafed924094c6' 
  AND token = '+H2W35jqDnZLTtkJDxA5fUl8NFRLRa9sYj20hMiLKEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}