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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0bd0146caba228ac4eb301695a342be8b6a2c9fe217c5855e9460f496bcba6' 
  AND token = 'ze1NlrovQZhNumik2K232lAXlXH5VFcE4wDetMXqMB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}