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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4baba26d9246d903f6931e46dc6ad9f00bb30ac006c44680b7f811594873d287' 
  AND token = 'u0ePRy5GLLmvpYLfFFmrWAwetArTrVLuUcamm4xtklE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}