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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd51f557e1a3b63436912b3d4a094abea5f1cf5441eb301a0ba1e6e017d7313f2' 
  AND token = '+L/teP0WtDwxTGkXFAFcjiekIWwWXtUXM01o493SAh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}