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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178a7eaaf597958c38cd2f71e3c39058580a4d561495fa6a2d1aed6cc4b19851' 
  AND token = 'ujgsTYpspHeGz1Wzu5gTxgJEvlQp8z1MdTfRq7+MrR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}