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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429b203d1b52d81f1a8783ad26ab5aa3d2e084e56b6e779ee4c6ab8eb696399f' 
  AND token = 'n8+9Oa73wJXuDzCZjpajZzcmj+uZfkI3PQZVycRM2Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}