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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bb0051b28084e88ff1c69f04cd71e26351936bdaa344176200b9826a5667051' 
  AND token = '78KH9IXS+xOsuiNpOTLlBlyOYPZ6/9jMZ3PyERE8SnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}