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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40442cf3c3b318b61513bad2764e06c78b46d729ce73f299ac72f957aa3b3030' 
  AND token = 'EkQrC2BcasHgD3IoMwwCok3ykOar6ygjuTH8OLU39xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}