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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7f953935c166dee5f1a91981c8058540e046d279a5034f0c4f523f09166877' 
  AND token = 'B/GGaw9PwAfPdyFJ4/DFgpKNBEeQDbmnM2Sa9P4Nkhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}