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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fe29780c21e7d188d849340b856a169e19dd6e44f1a937171206dbbb8bc972' 
  AND token = 'FMHKPyErCz9sG9bNO5NuDMAcLjylCPSerwesA6oL654=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}