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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9966a4403cc931f28d2406f51eeb9c61d100236d9d2b44d0f13787c77afe50b4' 
  AND token = '7AS3Y3LQsHbfrLhO5SeidPVF8MYVQJSL9ylgTqe/tJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}