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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '874eaf8335109c491565685c644c9b39c6e43911e94f39e141613f2ead966bb5' 
  AND token = 'M8T8ZIK0SR3OvWfM+XTUpwG2gMgY6KIqyg6S5XXP6X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}