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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6d34bfea2a92066e4ccfc261ab35dbe81064db01737a0d6f41dc9504546836' 
  AND token = 'QBPLQcdVFhqvqQrP5jpLQxQYpA3DDCrT2bOLKW9O7pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}