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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85052df1e3875e511d1733c2664a46ec56505576e9dc89a878d8c664caaa100' 
  AND token = 'n7xKmyhpF2I0Qwk0Wj6AZLpc5ntswo+qS5mRw6L9F7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}