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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e18f967ef61658969c0e4f6bcdcf337036d6d0e68654987055626433eff108' 
  AND token = 'dMGaFrY5YU9kugeDGHIWj6PHR33A6fNUMmRl5htELcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}