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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b96949bb2a2d2d95e15a818d0305822410e338d5e3b45f59a5eead866a4580' 
  AND token = 'konTDTPJXN+gaO5vLOfgXeFk+e/Wb3ZoH1p/S2hhSco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}