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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1819c2a5faf87e9f5c49d7c5a41d5aa00d72e354b51e31f7dca8043fab788fd9' 
  AND token = 'WZh4fcHM78ux0s+QW42jgEBha8ZaDcI2BfcHTd4+rZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}