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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfd8ef0ca3fad097fb602992c9451d1146d2ef1e2cd24b2d5b783ae4ca1103cd' 
  AND token = '9wVzaNSD/VHOn4jnNYRrj9CpYb8HJUUYbiXtWMH20oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}