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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ad3c60e434615d0b11277fab190a4e01bdd8486d8d96182c2ef5b46d31df9f' 
  AND token = 'QDFsL1K/kDp7Z0fR/UMX/NWv0+SWFbHunkk4UIiUi88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}