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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64eff0135a8e34d57f41d41af929e9515af8f28d6b5cc9ae28c1f2bf90db750f' 
  AND token = 'qvW+Gy3tg7Atu0sZsz8zWGonctkcyjSFHh2VWxr2Xi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}