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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8245a540af378264927ccb612e24d0117720efad353ac8c2eaaf436c1493a40a' 
  AND token = 'SvLV5locgzu4o6YccK4f0UgApNjmnMxKPnAn3XgLq0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}