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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05eb4d4f38a6c44ee2d4e0220e6ef8824e4d096414e32f4880c8321c68dddf4e' 
  AND token = 'leGWS+VNAlPfoWB29lOO65zj7FPY0Cp1AGF/3TgkeoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}