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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b29a1ede63e47ac7c7a00a4a363ee2d2bb3eb9a7984f1e56176fcb9f938b94' 
  AND token = 'Z34Q5lPgfNdjpjjxbz6GIqgFConajkMSfmj9LMNSvrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}