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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce148c26b1ea866e9055ab549204e151d09db52fde892f2816df12a0798766bf' 
  AND token = 'JG+XQlvZf2HJ9LBUvxrO+xDMs7TXOw2j0hJ5evuqbDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}